The iconic scene where Ham (Patrick Renna) asks Smalls (Tom Guiry) if he’d like a s’more took the longest to film for the 1993 movie The Sandlot.
Writer/Director/Narrator David Mickey Evans talked about the scene in a 2013 interview:
“Pat Renna was so damn funny saying ‘You’re killin’ me Smalls!’ That all the other guys busted up laughing every time he said it, and essentially rendered the take unusable because they were in the background. And when kid actors get the giggles, forget it, day over. They simply cannot stop laughing. Eventually (after hours and hours) I had to use a take in which I told the guys ‘look if you can’t stop laughing, just laugh with you r mouth closed!’ The take used in the movie, if you look at Benny in the background, poor Mike Vitar is actually biting his lip to keep from ruining the take.”
The scene and the “You’re Killing Me Smalls” quote has become so popular it has its own t-shirt.